Understanding Our Reports
MTHFR Support™ is proud to offer world class genetic reports that help people make important discissions about their personal health and the health of their family and friends.
Check out the videos below to you understand each report and how useful they can be to providing vital information about choosing the right treatments for their genetic mutations.
What is a variant report?
Welcome to MTHFR Support™.
In this video we will be introducing the variant report.
The variant report is one of our most popular cornerstone genetic reports.
With the variant report you can use your 23andme, Ancestry and many other raw data genetic files to create a gene report with over 1000+ genes.
With this powerful report you can gain significant insights to your health and genetic mutations.
When you purchase the variant report, the report is easily downloaded from Sterling’s App and you can save it as a PDF file.
The best place to work with your variant report is inside of Sterling’s app because you can interact with the report using the Tag search and SNP search.
However, using the report on its own is also very useful because of the amount of data available and your ability to quickly look up areas of interest to your health.
The variant report is a breakdown of all the genes that were tested by your ancestry provider.
The variant report breaks up your genes into useable data, for example, in this variant report there are 47 pages of genetics and an additional 11 pages with genetic pathway diagrams that help you with understanding the pathways for your genes and any mutations you may have.
The first thing to note is that your variant report shows your genes in three colours, the green genes mean there is no mutation, a yellow gene is considered a heterozygous gene mutation and a red gene is considered a homozygous gene mutation.
Often a yellow or heterozygous gene mutation is considered a half copy, that’s why you will see a +/- sign beside it, while a red or homozygous gene mutations can be considered as a doble copy with a +/+ sign beside it.
The next important part of the report is the heading topics. These headings in blue tell you what the genes you are looking at are associated with. As you can see the first topic heading covers Alzheimer’s, cardio and lipids.
As we scroll through to page 4 we now have a new topic, COMT Activity, you will also note that beside COMT Activity it says (Figure 1), this is to let you know that for all COMT genes there is a COMT pathway diagram that works with this section of the report.
To access the (Figure 1) COMT pathway diagram you simply click on the bookmarks tab of the variant report, this will then reveal all of the heading topics of the report and by scrolling down on the bookmarks menu and clicking on figure 1 you can now see the associated diagram that is associated with the COMT genes and their mutations.
Now you can see the COMT diagram you can see the flow of how the COMT gene works.
When you see that you have multiple gene mutations in COMT you can use this diagram to understand how you might be reacting with these mutations and work out what treatments, tests and ideas will work best for you.
As you can see looking through the bookmark section and all the titles, there is many useful ways to view your variant report including the more popular pathways including the methylation and homocysteine pathways, phase 1 and 2 liver detox, neurotransmitters, immunity and many more, including 11 advanced diagrams that make understanding your genetics much easier.
While the variant report is easy to use, especially inside Sterling’s App, we do recommend getting assistance from a practitioner who understands epigenetics and nutrigenomics.
What is a Methylation Report?
Welcome to MTHFR Support™.
In this video we will be introducing the methylation report.
The methylation report is a popular genetic report for understanding what gene mutations may be effecting your methylation cycle.
The methylation cycle is one of the most important factors as it relates to your overall health and wellbeing.
The methylation cycle is so important it can determine not only your level of health and wellbeing but it can also affect higher level concerns such as the production of your body’s most powerful antioxidants, the production of essential universal methyl donors that provide powerful detoxification processes. The methylation cycle also controls how your body rebuilds itself and ultimately, can control how fast you age and even determine how long you will live.
The first thing to note is that your methylation report shows your genes in three colours, the green genes mean there is no mutation, a yellow gene is considered a heterozygous gene mutation and a red gene is considered a homozygous gene mutation.
Often a yellow or heterozygous gene mutation is considered a half copy, that’s why you will see a +/- sign beside it, while a red or homozygous gene mutations can be considered as a double copy with a +/+ sign beside it.
One of the important markers of methylation called homocysteine, can provide some great insights to the overall health of your methylation cycle and it’s vital to understand that a homocysteine score that is too high can put you at risk of such things that can shorten your life span, equally a homocysteine score that is too low can also shorten your life span.
A good or optimal homocysteine score should be between 7 – 8 µmol/L. If your score is higher or lower, getting the methylation report can help to reveal why.
With the methylation report you can use your 23andme, Ancestry and many other raw data genetic files to create the methylation report.
With this powerful report you can gain significant insights to your genetic mutations that are associated directly with methylation and determine the correct treatment protocol to assist your methylation cycle and homocysteine to solve many health problems, improve detoxification and lower common risk factors.
The methylation report breaks up your genes into useable data, showing any gene mutations you may have in your methylation pathway that may be compromising your underlying health allowing you to solve current health problems and even getting ahead of a problem that is developing.
If you are trying to resolve an unknown health issue or solve problems associated with methylation, under-methylation and or over-methylation, the methylation report is a great way to help guide you to the associated gene mutations, it’s powerful and life saving.
While the methylation report is easy to use, especially inside Sterling’s App, we do recommend getting assistance from a practitioner who understands epigenetics and nutrigenomics.
What is the Excipient Report and how to use it
Welcome to MTHFR Support™.
In this video we will be introducing the excipient report.
The excipient report is a popular genetic report for understanding what substances including drugs, chemicals and food properties work with and or against your genes. With the excipient report you can use your 23andme, Ancestry and many other raw data genetic files to create the excipient gene report with over 1000+ genes.
With this powerful report you can gain significant insights to your genetic mutations with how various excipients have an effect on your wellbeing.
Excipients are substances added to food products, drugs, medications and nutritional supplements to enhance their physical and chemical properties. Food excipients can include preservatives, flavor enhancers, and nutrients, and are used to improve the flavor, texture, appearance, or nutritional value of food products.
The problem with excipients is that many people cannot tolerate them because of their gene mutations and can react in many ways negatively when excipients are consumed.
Often people can experience a wide range of symptoms from consuming excipients making it hard to understand what they did wrong to cause their reaction.
Symptoms of excipient reactions include skin rashes, gastrointestinal issues, and breathing problems. These reactions can be confused with allergic reactions or intolerances. Excipients can cause almost any negative response by influencing your immune system such as in mast cell activation.
Additionally, excipients can interact with neurotransmitters influencing how you feel and behave emotionally such as in anxiety, depression, A D H D, affecting the nervous system such as panic attacks and even cause functional problems such as heart beat regulation, sleep function, digestive function and mood dysregulation.
The excipient report is a breakdown of all the genes that were tested by your ancestry provider. The excipient report breaks up your genes into useable data, for example, in this report there are 76 pages of genetics and any gene mutations you may have for each of the excipients listed.
If you are trying to resolve an unknown health issue or reaction, use the excipient report to help find your culprit and associated gene mutations, its powerful and life saving.
